Cancer 1990 Apr 15;65(8):1843-6
Two different lymph node metastatic patterns of a prostatic cancer.
Saitoh H, Yoshida K, Uchijima Y, Kobayashi N, Suwata J, Kamata S.
Among 753 autopsy prostatic cancer cases with a metastasis, 476 (63%) had a
lymph node metastasis, whereas 277 (37%) did not. Two different lymph node
metastatic patterns were observed: Type 1, combined metastasis involving the
pelvic and paraaortic lymph nodes; and Type 2, metastasis to the paraaortic
lymph nodes, but not to the pelvic lymph nodes. Type 1 metastasis cases showed a
significantly more frequent metastasis to the bladder and rectum, and a less
frequent metastasis to the lungs and liver. Hydronephrosis occurred more
frequently (P less than 0.01) in the Type 1. Furthermore, in the Type 1 cases
the lymph node metastasis appeared to be continuously invasive, but in the Type
2 cases, metastasis appeared to be the skip type or some metastases may have
spread via the vertebral vein bypass route and may have been associated with a
hematogenous metastasis.
